Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.44 |
| ▸ | THRA | P10827 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918856 | 1.00 | PDK2 (0.44) | PDK2THRATHRBPTPN11NR5A1 | |
| SCHEMBL8921438 | 0.91 | PDK2 (0.39) | PDK2THRATHRBPTPN11NR5A1 | |
| SCHEMBL8918297 | 0.86 | PDK2 (0.39) | PDK2LMNA | |
| SCHEMBL8920315 | 0.85 | PDK2 (0.43) | PDK2THRATHRBPTPN11NR5A1 | |
| SCHEMBL8918861 | 0.85 | PDK2 (0.43) | PDK2THRATHRBPTPN11NR5A1 | |
| SCHEMBL8920583 | 0.81 | PDK2 (0.40) | PDK2THRATHRBPTPN11LMNA | |
| SCHEMBL7824752 | 0.80 | PDK2 (0.47) | PDK2THRATHRBPTPN11NR5A1 | |
| SCHEMBL7830265 | 0.80 | PDK2 (0.47) | PDK2THRATHRBPTPN11NR5A1 | |
| SCHEMBL7827212 | 0.78 | PDK2 (0.46) | PDK2THRATHRBPTPN11NR5A1 | |
| SCHEMBL7825985 | 0.78 | PDK2 (0.46) | PDK2THRATHRBPTPN11NR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691272-A | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5559247-A | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0679640-A1 | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-11-02 | — | — | EP | disclosed |