SCHEMBL8920314

SCHEMBL8920314

CCCCCC1CCC(C2CCC(C(C)c3ccc(F)c(F)c3)CC2)CC1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.32
SLC6A4 P31645 2/20 0.32
SLC6A3 Q01959 2/20 0.32
TP53 P04637 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
GCGR P47871 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9346831 1.00 SLC6A2 (0.32) SLC6A2SLC6A4SLC6A3TP53GAA
SCHEMBL10479991 0.93 SLC6A2 (0.32) SLC6A2SLC6A4SLC6A3TP53GAA
SCHEMBL10479519 0.91 TP53 (0.32) SLC6A2SLC6A4SLC6A3TP53GAA
SCHEMBL10479832 0.91 TP53 (0.32) SLC6A2SLC6A4SLC6A3TP53GAA
SCHEMBL9349806 0.91 SLC6A2 (0.34) SLC6A2SLC6A4SLC6A3CHRM3
SCHEMBL8435370 0.91 SLC6A2 (0.34) SLC6A2SLC6A4SLC6A3CHRM3
SCHEMBL10479744 0.89 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3MAPTCHRM3
SCHEMBL8961483 0.87 SLC6A2 (0.36) SLC6A2SLC6A4SLC6A3MAPTCHRM3
SCHEMBL8412601 0.86 GRM2 (0.36) SLC6A2SLC6A4SLC6A3TP53
SCHEMBL9349563 0.85 SLC6A2 (0.35) SLC6A2SLC6A4SLC6A3CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5696570-A TN cell having improved display of grey shades MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1997-12-09 US disclosed
EP-0393636-B1 Liquid crystal composition and liquid crystal display using said composition CHISSO CORP (JP) 1994-07-20 EP disclosed
US-5102577-A Supertwisted birefringence system CHISSO CORPORATION (JP) 1992-04-07 US disclosed
EP-0393636-A2 Liquid crystal composition and liquid crystal display using said composition CHISSO CORPORATION (JP) 1990-10-24 EP disclosed