Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10750543 | 0.92 | GRM2 (0.39) | GRM2SLC6A3SLC6A2DRD2DRD4 | |
| SCHEMBL10479592 | 0.91 | GRM2 (0.41) | GRM2SLC6A3SLC6A2DRD2DRD4 | |
| SCHEMBL10479922 | 0.91 | GRM2 (0.41) | GRM2SLC6A3SLC6A2DRD2DRD4 | |
| SCHEMBL8433409 | 0.90 | SLC6A3 (0.35) | SLC6A3 | |
| SCHEMBL10480046 | 0.88 | SLC6A3 (0.36) | GRM2SLC6A3SLC6A2DRD2DRD4 | |
| SCHEMBL8920314 | 0.86 | SLC6A2 (0.32) | SLC6A3SLC6A2SLC6A4TP53 | |
| SCHEMBL9346831 | 0.86 | SLC6A2 (0.32) | SLC6A3SLC6A2SLC6A4TP53 | |
| SCHEMBL9081652 | 0.84 | CYP2C9 (0.39) | SLC6A3SLC6A2DRD2DRD4DRD3 | |
| SCHEMBL8433891 | 0.84 | PDE2A (0.39) | SLC6A3SLC6A4 | |
| SCHEMBL7531700 | 0.82 | GRM2 (0.39) | GRM2SLC6A3SLC6A2DRD3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004479-A | FLUOROETHERS FOR LIQUID CRYSTAL DISPLAYS AND DIELECTRICS | MERCK KGAA (DE) | 1999-12-21 | — | — | US | disclosed |
| US-5876626-A | HIGH SPEED SWITCHING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-03-02 | — | — | US | disclosed |
| EP-0394417-B1 | SUPERTWIST LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 1994-10-26 | — | — | EP | disclosed |
| EP-0394417-A1 | SUPERTWIST LIQUID CRYSTAL DISPLAY. | MERCK PATENT GMBH (DE) | 1990-10-31 | — | — | EP | disclosed |