Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.57 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 11/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922199 | 1.00 | ENPP2 (0.57) | ENPP2DGAT2HDAC1HDAC6HDAC3 | |
| SCHEMBL8920548 | 1.00 | ENPP2 (0.57) | ENPP2DGAT2HDAC1HDAC6HDAC3 | |
| SCHEMBL8920738 | 1.00 | ENPP2 (0.57) | ENPP2DGAT2HDAC1HDAC6HDAC3 | |
| SCHEMBL8921799 | 1.00 | ENPP2 (0.57) | ENPP2DGAT2HDAC1HDAC6HDAC3 | |
| SCHEMBL8920494 | 1.00 | ENPP2 (0.57) | ENPP2DGAT2HDAC1HDAC6HDAC3 | |
| SCHEMBL8921079 | 1.00 | ENPP2 (0.57) | ENPP2DGAT2HDAC1HDAC6HDAC3 | |
| SCHEMBL8923152 | 1.00 | ENPP2 (0.57) | ENPP2DGAT2HDAC1HDAC6HDAC3 | |
| SCHEMBL8921546 | 1.00 | ENPP2 (0.57) | ENPP2DGAT2HDAC1HDAC6HDAC3 | |
| SCHEMBL8921731 | 1.00 | ENPP2 (0.57) | ENPP2DGAT2HDAC1HDAC6HDAC3 | |
| SCHEMBL8924599 | 1.00 | ENPP2 (0.57) | ENPP2DGAT2HDAC1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670493-A | ANGIOGENESIS INHIBITORS | ADIR ET COMPAGNIE (FR) | 1997-09-23 | — | — | US | disclosed |