Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 13/20 | 0.53 |
| ▸ | ELANE | P08246 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921575 | 1.00 | CMA1 (0.53) | CMA1ELANETSHRPOLBKMT2A | |
| SCHEMBL23969584 | 0.89 | CMA1 (0.59) | CMA1ELANETSHR | |
| SCHEMBL7860727 | 0.89 | ELANE (0.55) | CMA1ELANE | |
| SCHEMBL8611726 | 0.88 | XIAP (0.47) | CMA1ELANEPOLBXIAP | |
| SCHEMBL8922544 | 0.88 | XIAP (0.47) | CMA1ELANEPOLBXIAP | |
| SCHEMBL10297427 | 0.88 | CMA1 (0.49) | CMA1ELANEXIAP | |
| SCHEMBL10297464 | 0.88 | CMA1 (0.49) | CMA1ELANEXIAP | |
| SCHEMBL6374299 | 0.86 | CMA1 (0.49) | CMA1ELANE | |
| SCHEMBL8922480 | 0.86 | PREP (0.49) | CMA1ELANEXIAP | |
| SCHEMBL8961236 | 0.86 | PREP (0.49) | CMA1ELANEXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616573-A | Glucocorticoids | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |
| EP-0693080-A1 | NEW GLUCOCORTICOIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994022898-A1 | NEW GLUCOCORTICOIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-10-13 | — | — | WO | disclosed |