Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8498381 | 0.90 | ELANE (0.63) | ELANECMA1 | |
| SCHEMBL8920472 | 0.89 | CMA1 (0.53) | ELANECMA1 | |
| SCHEMBL8921575 | 0.89 | CMA1 (0.53) | ELANECMA1 | |
| SCHEMBL6374299 | 0.88 | CMA1 (0.49) | ELANECMA1 | |
| SCHEMBL10297464 | 0.85 | CMA1 (0.49) | ELANECMA1 | |
| SCHEMBL10297427 | 0.85 | CMA1 (0.49) | ELANECMA1 | |
| SCHEMBL8630185 | 0.85 | CMA1 (0.51) | ELANECMA1 | |
| SCHEMBL8053347 | 0.85 | ELANE (0.56) | ELANECMA1 | |
| SCHEMBL8053356 | 0.85 | ELANE (0.56) | ELANECMA1 | |
| SCHEMBL7337411 | 0.84 | ELANE (0.62) | ELANECMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0762887-B1 | ACYLATED ENOL DERIVATIVES AS PRODRUGS OF ELASTASE INHIBITORS | MERRELL PHARMA INC (US) | 2001-09-26 | — | — | EP | disclosed |
| US-6130315-A | SUBSTRATES IN WHICH THE SCISSILE AMIDE BOND HAS BEEN REPLACED BY AN ACTIVATED ELECTROPHILIC KETONE MOIETY; ANTIINFLAMMATORY AGENTS; ANTIPROLIFERATIVE/ANTICARCINOGENIC/ANTIARTHRITIC AGENTS; TREATMENT OF AUTOIMMUNE DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 2000-10-10 | — | — | US | disclosed |
| US-5972897-A | AN ANTIINFLAMMATORY AGENTS TREATING CYSTIC FIBROSIS AND EMPHYSEMA OR BOWEL DISEASES, A NEUTROPHIL ASSOCIATED INFLAMMATORY DISEASE, BRONCHITIS | MERRELL PHARMACEUTICALS INC. (US) | 1999-10-26 | — | — | US | disclosed |
| US-5496927-A | INHIBITORS OF HUMAN LEUKOCYTE ELASTASE, CATHEPSIN G, CHYMOTRYPSIN | MERRELL PHARMACEUTICALS INC. (US) | 1996-03-05 | — | — | US | disclosed |
| EP-0195212-B1 | Novel peptidase inhibitors | MERRELL DOW PHARMA (US) | 1993-11-24 | — | — | EP | disclosed |