Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.45 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.45 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.45 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.45 |
| ▸ | CBFB | Q13951 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29594647 | 1.00 | TDP1 (0.53) | TDP1ALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL11772594 | 0.86 | TDP1 (0.53) | TDP1ALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL28728891 | 0.82 | TDP1 (0.49) | TDP1ALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL29593583 | 0.82 | TDP1 (0.49) | TDP1ALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL8780994 | 0.81 | PKM (0.56) | TDP1ALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL4055616 | 0.80 | TDP1 (0.57) | TDP1ALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL2962034 | 0.80 | KDM4E (0.55) | TDP1ALDH1A1KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL7509092 | 0.80 | TDP1 (0.60) | TDP1ALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL30442658 | 0.80 | TDP1 (0.60) | TDP1ALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL2964139 | 0.79 | HDAC1 (0.47) | TDP1ALDH1A1KDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672759-A | BOARD RANGE OF SHADES OF COLOR EXHIBIT LIGHT RESISTANCE, WASHFASTNESS, WEATHERPROOFING AND RESISTANCE TO VARIOUS TREATMENT TO WHICH HAIR MAY BE SUBJECTED | L'OREAL (FR) | 1997-09-30 | — | — | US | claimed |
| US-5534037-A | Dye composition for keratinic fibres containing sulfured metaphenylenediamines, dyeing process and new sulfured metaphenylenediamines and preparation method thereof | L'OREAL (FR) | 1996-07-09 | — | — | US | claimed |
| EP-0586648-B1 | DYE COMPOSITION FOR KERATINIC FIBRES CONTAINING SULFURED METAPHENYLENEDIAMINES, DYEING PROCESS AND NEW SULFURED METAPHENYLENEDIAMINES AND PREPARATION METHOD THEREOF | OREAL (FR) | 1995-12-06 | — | — | EP | claimed |
| CN-114394974-A | Polysubstituted triaryl macrocyclic compounds and uses thereof | 中国药科大学 | 2022-04-26 | — | — | CN | disclosed |
| US-5672759-A | BOARD RANGE OF SHADES OF COLOR EXHIBIT LIGHT RESISTANCE, WASHFASTNESS, WEATHERPROOFING AND RESISTANCE TO VARIOUS TREATMENT TO WHICH HAIR MAY BE SUBJECTED | L'OREAL (FR) | 1997-09-30 | — | — | US | disclosed |
| US-5534037-A | Dye composition for keratinic fibres containing sulfured metaphenylenediamines, dyeing process and new sulfured metaphenylenediamines and preparation method thereof | L'OREAL (FR) | 1996-07-09 | — | — | US | disclosed |
| EP-0586648-B1 | DYE COMPOSITION FOR KERATINIC FIBRES CONTAINING SULFURED METAPHENYLENEDIAMINES, DYEING PROCESS AND NEW SULFURED METAPHENYLENEDIAMINES AND PREPARATION METHOD THEREOF | OREAL (FR) | 1995-12-06 | — | — | EP | disclosed |
| EP-0586648-A1 | DYE COMPOSITION FOR KERATINIC FIBRES CONTAINING SULFURED METAPHENYLENEDIAMINES, DYEING PROCESS AND NEW SULFURED METAPHENYLENEDIAMINES AND PREPARATION METHOD THEREOF. | OREAL (FR) | 1994-03-16 | — | — | EP | disclosed |
| WO-1993016990-A1 | DYE COMPOSITION FOR KERATINIC FIBRES CONTAINING SULFURED METAPHENYLENEDIAMINES, DYEING PROCESS AND NEW SULFURED METAPHENYLENEDIAMINES AND PREPARATION METHOD THEREOF | L'OREAL (FR) | 1993-09-02 | — | — | WO | disclosed |