SCHEMBL8920536

SCHEMBL8920536

CC(C)(C)NC(=O)CN1C(=O)C(NC(=O)Nc2cccc(Cl)c2)CC(c2ccccc2)c2cc(Cl)ccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8921202 0.95 CCKBR (0.90) CCKBR
SCHEMBL8924443 0.95 CCKBR (1.00) CCKBR
SCHEMBL8485760 0.94 CCKBR (1.00) CCKBR
SCHEMBL8922094 0.92 CCKBR (0.92) CCKBR
SCHEMBL8920715 0.91 CCKBR (0.84) CCKBR
SCHEMBL8920787 0.91 CCKBR (1.00) CCKBR
SCHEMBL8920927 0.91 CCKBR (1.00) CCKBR
SCHEMBL8922090 0.89 CCKBR (0.90) CCKBR
SCHEMBL8919527 0.89 CCKBR (0.90) CCKBR
SCHEMBL8920510 0.88 CCKBR (0.88) CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5643904-A Substituted hexahdryoazepinones and tetrahydrobenzazepinones PFIZER INC. (US) 1997-07-01 US disclosed