SCHEMBL9348258

SCHEMBL9348258

ClCCOc1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.46
TDP1 Q9NUW8 2/20 0.46
PLAU P00749 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
S1PR4 O95977 1/20 0.39
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 2/20 0.38
TSHR P16473 2/20 0.38
HPGD P15428 2/20 0.36
MAPK1 P28482 1/20 0.36
ORAI1 Q96D31 1/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CYP1A2 P05177 1/20 0.35
AHR P35869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21854480 0.82 CYP3A4 (0.42) MAPTTDP1PLAUL3MBTL1CA1
SCHEMBL2799797 0.82 MAPT (0.53) MAPTTDP1PLAUL3MBTL1SMN1; SMN2
SCHEMBL11376213 0.80 CA1 (0.41) MAPTTDP1PLAUL3MBTL1SMN1; SMN2
SCHEMBL8920540 0.79 MAPT (0.45) MAPTTDP1PLAUL3MBTL1SMN1; SMN2
SCHEMBL13261204 0.79 MAPT (0.49) MAPTTDP1PLAUL3MBTL1SMN1; SMN2
SCHEMBL9622239 0.79 PLAU (0.61) MAPTTDP1PLAUL3MBTL1SMN1; SMN2
SCHEMBL9349699 0.79 MAPT (0.45) MAPTTDP1PLAUL3MBTL1SMN1; SMN2
SCHEMBL9324460 0.79 MAPT (0.45) MAPTTDP1PLAUL3MBTL1SMN1; SMN2
SCHEMBL23573767 0.77 PLAU (0.38) MAPTTDP1PLAUL3MBTL1KDM4E
Hydrochloric Acid SCHEMBL10442699 0.77 PLAU (0.59) MAPTTDP1PLAUL3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116332732-B Preparation method of 2- (2, 4, 6-trichlorophenoxy) ethyl chloride 台州学院 2024-11-05 CN claimed
CN-116332732-A Preparation method of 2- (2, 4, 6-trichlorophenoxy) ethyl chloride 台州学院 2023-06-27 CN claimed
WO-2023108677-A1 METHOD FOR PREPARING 2-(2,4,6-TRICHLOROPHENOXY)ETHYL CHLORIDE 台州学院 2023-06-22 WO claimed
CN-101851167-B Method for synthesizing prochloraz intermediate UNIV WENZHOU 2013-04-17 CN claimed
CN-101851166-B Synthesis method for prochloraz intermediate UNIV WENZHOU 2013-04-17 CN claimed
EP-0403929-B1 A method of preparing phenoxy ethers for use as agrochemical intermediates MAKHTESHIM CHEM WORKS LTD (IL) 1994-08-31 EP claimed
EP-0404092-B1 A novel method of preparing phenoxy ethers for use as agrochemical intermediates MAKHTESHIM CHEM WORKS LTD (IL) 1994-08-31 EP claimed
US-5091577-A METHOD OF PREPARING FUNGICIDAL INTERMEDIATES MAKHTESHIM CHEMICAL WORKS LTD. (IL) 1992-02-25 US claimed
US-5091578-A METHOD OF PREPARING PHENOXY ETHERS FOR USE AS AGROCHEMICAL INTERMEDIATES MAKHTESHIM CHEMICAL WORKS LTD. (IL) 1992-02-25 US claimed
EP-0404092-A2 A novel method of preparing phenoxy ethers for use as agrochemical intermediates MAKHTESHIM CHEMICAL WORKS LIMITED (IL) 1990-12-27 EP claimed
EP-0403929-A2 A method of preparing phenoxy ethers for use as agrochemical intermediates MAKHTESHIM CHEMICAL WORKS LIMITED (IL) 1990-12-27 EP claimed
CN-116332732-B Preparation method of 2- (2, 4, 6-trichlorophenoxy) ethyl chloride 台州学院 2024-11-05 CN disclosed
CN-116332732-B Preparation method of 2- (2, 4, 6-trichlorophenoxy) ethyl chloride 台州学院 2024-11-05 CN disclosed
CN-116332732-B Preparation method of 2- (2, 4, 6-trichlorophenoxy) ethyl chloride 台州学院 2024-11-05 CN disclosed
CN-116332732-A Preparation method of 2- (2, 4, 6-trichlorophenoxy) ethyl chloride 台州学院 2023-06-27 CN disclosed
EP-0404092-A3 A NOVEL METHOD OF PREPARING PHENOXY ETHERS FOR USE AS AGROCHEMICAL INTERMEDIATES MAKHTESHIM CHEMICAL WORKS LIMITED (IL) 1992-02-12 EP disclosed
EP-0404092-A2 A novel method of preparing phenoxy ethers for use as agrochemical intermediates MAKHTESHIM CHEMICAL WORKS LIMITED (IL) 1990-12-27 EP disclosed
EP-0404092-A2 A novel method of preparing phenoxy ethers for use as agrochemical intermediates MAKHTESHIM CHEMICAL WORKS LIMITED (IL) 1990-12-27 EP disclosed
EP-0403929-A2 A method of preparing phenoxy ethers for use as agrochemical intermediates MAKHTESHIM CHEMICAL WORKS LIMITED (IL) 1990-12-27 EP disclosed
EP-0403929-A2 A method of preparing phenoxy ethers for use as agrochemical intermediates MAKHTESHIM CHEMICAL WORKS LIMITED (IL) 1990-12-27 EP disclosed