Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.49 |
| ▸ | SELE | P16581 | 2/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6652985 | 0.89 | ICAM1 (0.51) | EDNRAICAM1SELEVCAM1L3MBTL1 | |
| SCHEMBL6995489 | 0.84 | EDNRA (0.54) | EDNRAICAM1SELEVCAM1L3MBTL1 | |
| SCHEMBL30724572 | 0.82 | ICAM1 (0.58) | EDNRAICAM1SELEVCAM1L3MBTL1 | |
| SCHEMBL9362508 | 0.82 | EDNRA (0.52) | EDNRAICAM1SELEVCAM1L3MBTL1 | |
| SCHEMBL6652136 | 0.80 | PTPN2 (0.52) | EDNRAKDM4EALDH1A1LMNAPTPN1 | |
| SCHEMBL9374943 | 0.80 | EDNRA (0.71) | EDNRAICAM1SELEVCAM1L3MBTL1 | |
| SCHEMBL5219829 | 0.76 | EDNRA (0.54) | EDNRAICAM1SELEVCAM1L3MBTL1 | |
| SCHEMBL5040288 | 0.76 | ICAM1 (0.78) | EDNRAICAM1SELEVCAM1L3MBTL1 | |
| SCHEMBL5212761 | 0.74 | ICAM1 (0.50) | EDNRAICAM1SELEVCAM1L3MBTL1 | |
| SCHEMBL5212677 | 0.74 | RXFP1 (0.60) | EDNRAICAM1SELEVCAM1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703069-A | USING (THIA, OXA, OR DI)AZEPINONE COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1997-12-30 | — | — | US | disclosed |