SCHEMBL8920618

SCHEMBL8920618

COC(=O)C[C@H](OCc1ccccc1)[C@H](O)COCc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.51
ABCB1 P08183 2/20 0.47
NPC1 O15118 1/20 0.46
CA1 P00915 3/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
MMP2 P08253 1/20 0.41
MMP3 P08254 1/20 0.41
HTT P42858 1/20 0.41
TACR1 P25103 2/20 0.41
SLC1A1 P43005 1/20 0.41
MMP1 P03956 1/20 0.40
REN P00797 1/20 0.40
MAOB P27338 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7423196 0.81 CA1 (0.57) KMT2AABCB1NPC1CA1CA2
SCHEMBL3680778 0.81 CA1 (0.57) KMT2AABCB1NPC1CA1CA2
SCHEMBL3680781 0.81 CA1 (0.57) KMT2AABCB1NPC1CA1CA2
SCHEMBL14429284 0.81 KMT2A (0.43) KMT2AABCB1CA1CA2CA7
SCHEMBL22571978 0.81 CA1 (0.54) KMT2ACA1CA2CA7CA9
SCHEMBL8921738 0.80 CA1 (0.42) KMT2ANPC1CA1CA2CA7
SCHEMBL21283007 0.79 KMT2A (0.42) KMT2AABCB1CA1CA2CA7
SCHEMBL20233630 0.79 KMT2A (0.47) KMT2AABCB1NPC1CA1CA2
SCHEMBL14747305 0.78 CA1 (0.51) KMT2ACA1CA2CA7CA9
SCHEMBL5694054 0.78 CA1 (0.51) KMT2ACA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5703224-A Antiviral c-nucleoside derivatives NIPPON SHINYAKU CO. LTD. (JP) 1997-12-30 US disclosed
EP-0733630-A1 NUCLEOSIDE DERIVATIVE NIPPON SHINYAKU COMPANY, LIMITED (JP) 1996-09-25 EP disclosed