Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14429284 | 0.93 | KMT2A (0.43) | KMT2AGHSRFOLH1KDM4EALDH1A1 | |
| SCHEMBL18868656 | 0.91 | KMT2A (0.43) | KMT2AGHSRFOLH1KDM4EALDH1A1 | |
| SCHEMBL14429285 | 0.83 | FOLH1 (0.50) | KMT2AFOLH1HTTTACR1CA1 | |
| SCHEMBL5981451 | 0.83 | KMT2A (0.44) | KMT2AHTTTACR1CA1CA2 | |
| SCHEMBL18868658 | 0.82 | LMNA (0.44) | GHSRFOLH1KDM4EALDH1A1LMNA | |
| SCHEMBL23398110 | 0.81 | KDM4E (0.41) | GHSRFOLH1KDM4EALDH1A1LMNA | |
| SCHEMBL8920618 | 0.79 | KMT2A (0.51) | KMT2AHTTTACR1CA1CA2 | |
| SCHEMBL12636372 | 0.79 | KMT2A (0.50) | KMT2AHTTTACR1CA1CA2 | |
| SCHEMBL9837878 | 0.79 | CA1 (0.45) | KMT2AHTTTACR1CA1CA2 | |
| SCHEMBL18868661 | 0.79 | LMNA (0.43) | KDM4EALDH1A1LMNACA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10723750-B2 | Sphingamide compounds and methods for binding iNKT cells | LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) | 2020-07-28 | — | — | US | disclosed |
| US-20190256541-A1 | SPHINGAMIDE COMPOUNDS AND METHODS FOR BINDING iNKT CELLS | LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) | 2019-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10723750-B2 | Sphingamide compounds and methods for binding iNKT cells | UGCG, CD4, CERT1 | KMT2A 603/4885GHSR 954/4885FOLH1 1855/4885 |
| US-20190256541-A1 | SPHINGAMIDE COMPOUNDS AND METHODS FOR BINDING iNKT CELLS | UGCG, CD4, CERT1 | KMT2A 603/4885GHSR 954/4885FOLH1 1855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.