Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 17/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921243 | 0.94 | CCKBR (0.54) | CCKBRKMT2A | |
| SCHEMBL8922427 | 0.93 | CCKBR (0.45) | CCKBR | |
| SCHEMBL8922472 | 0.93 | CCKBR (0.47) | CCKBR | |
| SCHEMBL8922642 | 0.90 | CCKBR (0.56) | CCKBR | |
| SCHEMBL8921193 | 0.90 | CCKBR (0.48) | CCKBRKMT2A | |
| SCHEMBL8921420 | 0.90 | CCKBR (0.52) | CCKBR | |
| SCHEMBL8922632 | 0.85 | CCKBR (0.61) | CCKBR | |
| SCHEMBL8919501 | 0.85 | CCKBR (0.53) | CCKBR | |
| SCHEMBL8920308 | 0.83 | CCKBR (0.55) | CCKBR | |
| SCHEMBL8920615 | 0.82 | CCKBR (0.57) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643904-A | Substituted hexahdryoazepinones and tetrahydrobenzazepinones | PFIZER INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5484917-A | FOR TREATMENT AND PREVENTION OF GASTROINTESTINAL DISORDERS, PAIN AND ANXIETY | PFIZER INC. (US) | 1996-01-16 | — | — | US | disclosed |
| WO-1993015059-A1 | 3-PHENYLUREIDO-AZEPIN-2-ONES AND -BENZAZEPIN-2-ONES USEFUL AS CHOLECYSTOKININ ANTAGONISTS | PFIZER INC. (US) | 1993-08-05 | — | — | WO | disclosed |