Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920930 | 1.00 | KMT2A (0.63) | KMT2APOLBL3MBTL1TDP1HCAR2 | |
| SCHEMBL17491875 | 0.91 | POLB (0.56) | KMT2APOLBL3MBTL1TDP1HCAR2 | |
| SCHEMBL17491876 | 0.91 | POLB (0.56) | KMT2APOLBL3MBTL1TDP1HCAR2 | |
| SCHEMBL17491864 | 0.85 | KMT2A (0.54) | KMT2APOLBL3MBTL1TDP1HCAR2 | |
| SCHEMBL14300687 | 0.85 | MAOA (0.58) | KMT2APOLBL3MBTL1TDP1HCAR2 | |
| SCHEMBL2720405 | 0.85 | MAPT (0.74) | KMT2APOLBL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL2720407 | 0.85 | MAPT (0.74) | KMT2APOLBL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL17491863 | 0.85 | KMT2A (0.54) | KMT2APOLBL3MBTL1TDP1HCAR2 | |
| SCHEMBL14300686 | 0.85 | MAOA (0.58) | KMT2APOLBL3MBTL1TDP1HCAR2 | |
| SCHEMBL5520871 | 0.82 | KMT2A (0.51) | KMT2APOLBL3MBTL1TDP1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1063182-C | New aminophenylphosphonic acid compounds, process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 2001-03-14 | — | — | CN | disclosed |
| US-5670493-A | ANGIOGENESIS INHIBITORS | ADIR ET COMPAGNIE (FR) | 1997-09-23 | — | — | US | disclosed |
| CN-1145908-A | New aminophenylphosphonic acid compounds, process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 1997-03-26 | — | — | CN | disclosed |
| US-4093622-A | Pyridine esters of cyclopropane-carboxylic acid | ZOECON CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |