Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919532 | 0.90 | SLC18A3 (0.40) | SRD5A1AKR1C3AKR1C1DDB1CRBN | |
| SCHEMBL13039616 | 0.82 | SRD5A1 (0.47) | SRD5A1AKR1C3AKR1C1MAPTGAA | |
| SCHEMBL7876855 | 0.82 | DDB1 (0.43) | SRD5A1DDB1CRBNSIGMAR1 | |
| SCHEMBL13210441 | 0.81 | DDB1 (0.57) | SRD5A1DDB1CRBNMAPTGAA | |
| SCHEMBL3460426 | 0.79 | SRD5A1 (0.45) | SRD5A1AKR1C3AKR1C1DDB1CRBN | |
| SCHEMBL18585014 | 0.79 | SRD5A1 (0.49) | SRD5A1AKR1C3AKR1C1MAPTGAA | |
| SCHEMBL22048164 | 0.79 | SRD5A1 (0.45) | SRD5A1AKR1C3AKR1C1DDB1CRBN | |
| SCHEMBL22321333 | 0.79 | SRD5A1 (0.45) | SRD5A1AKR1C3AKR1C1DDB1CRBN | |
| SCHEMBL11475323 | 0.79 | MT-CO2 (0.46) | SRD5A1DDB1CRBNSIGMAR1ALDH1A1 | |
| SCHEMBL11796468 | 0.79 | DDB1 (0.43) | AKR1C3AKR1C1DDB1CRBNMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016104954-A2 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | 주식회사 두산 | 2016-06-30 | — | — | WO | disclosed |
| WO-2016104954-A2 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | 주식회사 두산 | 2016-06-30 | — | — | WO | disclosed |
| US-5643904-A | Substituted hexahdryoazepinones and tetrahydrobenzazepinones | PFIZER INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5484917-A | FOR TREATMENT AND PREVENTION OF GASTROINTESTINAL DISORDERS, PAIN AND ANXIETY | PFIZER INC. (US) | 1996-01-16 | — | — | US | disclosed |
| WO-1993015059-A1 | 3-PHENYLUREIDO-AZEPIN-2-ONES AND -BENZAZEPIN-2-ONES USEFUL AS CHOLECYSTOKININ ANTAGONISTS | PFIZER INC. (US) | 1993-08-05 | — | — | WO | disclosed |