Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29016897 | 0.81 | DDB1 (0.61) | DDB1CRBNHSD11B1CYP19A1MAOB | |
| SCHEMBL31147295 | 0.79 | SRD5A1 (0.43) | SRD5A1AKR1C3AKR1C1 | |
| SCHEMBL8676176 | 0.79 | MT-CO2 (0.49) | DDB1CRBNHSD11B1ALDH1A1CYP19A1 | |
| SCHEMBL5845789 | 0.79 | DDB1 (0.47) | DDB1CRBNHSD11B1CYP19A1MAOB | |
| SCHEMBL7739386 | 0.79 | SRD5A1 (0.38) | SRD5A1AKR1C3AKR1C1ALDH1A1SLC18A3 | |
| SCHEMBL11701944 | 0.77 | KDM4E (0.46) | SRD5A1AKR1C3AKR1C1ALDH1A1POLB | |
| SCHEMBL11777020 | 0.76 | DDB1 (0.45) | DDB1CRBNHSD11B1CYP19A1MAOB | |
| SCHEMBL22321333 | 0.76 | SRD5A1 (0.45) | DDB1CRBNSRD5A1AKR1C3AKR1C1 | |
| SCHEMBL13039616 | 0.75 | SRD5A1 (0.47) | SRD5A1AKR1C3AKR1C1HPGDMAOB | |
| SCHEMBL28391454 | 0.75 | DDB1 (0.44) | DDB1CRBNHSD11B1TSHRCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107338043-B | Novel racemic chiral organic boron-nitrogen fluorescent compound and preparation method thereof | 湖南大学 | 2020-04-24 | — | — | CN | disclosed |
| CN-107338043-A | A kind of new racemic chirality organic boron nitrogen fluorescent chemicals and preparation method thereof | 湖南大学 | 2017-11-10 | — | — | CN | disclosed |
| US-5643904-A | Substituted hexahdryoazepinones and tetrahydrobenzazepinones | PFIZER INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5484917-A | FOR TREATMENT AND PREVENTION OF GASTROINTESTINAL DISORDERS, PAIN AND ANXIETY | PFIZER INC. (US) | 1996-01-16 | — | — | US | disclosed |
| EP-0625145-A1 | 3-PHENYLUREIDO-AZEPIN-2-ONES AND -BENZAZEPIN-2-ONES USEFUL AS CHOLECYSTOKININ ANTAGONISTS | PFIZER INC. (US) | 1994-11-23 | — | — | EP | disclosed |
| WO-1993015059-A1 | 3-PHENYLUREIDO-AZEPIN-2-ONES AND -BENZAZEPIN-2-ONES USEFUL AS CHOLECYSTOKININ ANTAGONISTS | PFIZER INC. (US) | 1993-08-05 | — | — | WO | disclosed |