Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SRC | P12931 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921066 | 1.00 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL13170385 | 0.93 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL13170473 | 0.93 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL12244182 | 0.82 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL29641676 | 0.82 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL8920599 | 0.82 | TTR (0.59) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL8920587 | 0.82 | TTR (0.59) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL8487131 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL3221525 | 0.81 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL12244180 | 0.81 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670493-A | ANGIOGENESIS INHIBITORS | ADIR ET COMPAGNIE (FR) | 1997-09-23 | — | — | US | disclosed |