Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | DPP4 | P27487 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | FDPS | P14324 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920599 | 1.00 | TTR (0.59) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL8921066 | 0.82 | KDM4E (0.53) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL8921074 | 0.82 | KDM4E (0.53) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL10939791 | 0.78 | CA12 (0.86) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL5059085 | 0.78 | CA12 (0.86) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL13957401 | 0.78 | CA12 (0.86) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL12244182 | 0.78 | KDM4E (0.63) | SRCKDM4EPOLBPKMHTT | |
| SCHEMBL29641676 | 0.78 | KDM4E (0.63) | SRCKDM4EPOLBPKMHTT | |
| SCHEMBL11217092 | 0.77 | TTR (0.71) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL11217091 | 0.77 | TTR (0.71) | TTRDPP4CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670493-A | ANGIOGENESIS INHIBITORS | ADIR ET COMPAGNIE (FR) | 1997-09-23 | — | — | US | disclosed |