Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MLNR | O43193 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3880017 | 0.79 | CYP19A1 (0.64) | CYP19A1KDM4EMEN1MLNRLMNA | |
| SCHEMBL3237240 | 0.78 | CYP19A1 (0.64) | CYP19A1KDM4EMEN1MLNRLMNA | |
| SCHEMBL3247619 | 0.77 | CYP19A1 (0.72) | CYP19A1KDM4EMEN1MLNRLMNA | |
| Cyclohexane SCHEMBL9501557 | 0.77 | CYP19A1 (0.57) | CYP19A1KDM4EMEN1MLNRLMNA | |
| SCHEMBL1817741 | 0.76 | HTT (0.41) | MEN1CYP1A2CYP3A4MAPTCYP2C9 | |
| SCHEMBL2307589 | 0.76 | CYP19A1 (0.59) | CYP19A1KDM4EMEN1MLNRLMNA | |
| SCHEMBL10658813 | 0.75 | CYP19A1 (0.61) | CYP19A1KDM4EMEN1MLNRLMNA | |
| SCHEMBL16389747 | 0.75 | ALDH1A1 (0.56) | KDM4EMEN1LMNACYP1A2MAPT | |
| SCHEMBL5185903 | 0.75 | ALDH1A1 (0.54) | KDM4EMEN1HPGDTSHRPTGS1 | |
| SCHEMBL1819681 | 0.75 | HTT (0.39) | CYP19A1KDM4ELMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |