SCHEMBL8921497

SCHEMBL8921497

C=CCC(C(=C)C(N)=O)C(N)=O

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.34
GRIK2 Q13002 2/20 0.34
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
FGFR4 P22455 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8927709 0.85 GRIK1 (0.37) GRIK1GRIK2
SCHEMBL6131545 0.84 GRIK1 (0.40) GRIK1GRIK2ALDH1A1TSHRFGFR4
SCHEMBL1417130 0.76 GRIK1 (0.35) GRIK1GRIK2ALDH1A1TSHRFGFR4
SCHEMBL28326500 0.71 CYP2C19 (0.35) GRIK1GRIK2
SCHEMBL5282308 0.70 CA1 (0.38) GRIK1GRIK2TSHR
SCHEMBL174976 0.69 GRIK1 (0.50) GRIK1GRIK2ALDH1A1TSHRFGFR4
SCHEMBL253739 0.68 GRIK1 (0.41) GRIK1GRIK2
SCHEMBL31636 0.68 GRIK1 (0.48) GRIK1GRIK2ALDH1A1TSHR
SCHEMBL17672253 0.67 TDP1 (0.41)
SCHEMBL11763944 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5658701-A PROVIDING PEELABLE TRANSFER LAYER CONTAINING THERMOPLASTIC RESIN ON SURFACE OF ELECTROGRAPHIC LIGHT SENSITIVE ELEMENT, FORMING NON-FIXING TONER IMAGE, TRANSFERRING TO RECEPTOR, THEN TO SUPPORT, REMOVING NONTACKY RESIN LAYER FROM IMAGE FUJI PHOTO FILM CO., LTD. (JP) 1997-08-19 US disclosed