Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417130 | 0.85 | GRIK1 (0.35) | GRIK1GRIK2CYP2C19TSHRALDH1A1 | |
| SCHEMBL28326500 | 0.85 | CYP2C19 (0.35) | GRIK1GRIK2CYP2C19MAPT | |
| SCHEMBL8921497 | 0.84 | GRIK1 (0.34) | GRIK1GRIK2TSHRALDH1A1FGFR4 | |
| SCHEMBL8927709 | 0.82 | GRIK1 (0.37) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL174976 | 0.78 | GRIK1 (0.50) | GRIK1GRIK2CYP2C19TSHRALDH1A1 | |
| SCHEMBL31636 | 0.77 | GRIK1 (0.48) | GRIK1GRIK2CYP2C19TSHRALDH1A1 | |
| SCHEMBL6449828 | 0.76 | — | — | |
| SCHEMBL8251491 | 0.76 | — | — | |
| SCHEMBL1045132 | 0.76 | — | — | |
| SCHEMBL11763944 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021099336-A1 | METHOD FOR IMPROVING COEFFICIENT OF FRICTION IN CURED FLUORORUBBER PARTS | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2021-05-27 | — | — | WO | claimed |
| EP-1343837-A1 | FLUOROELASTOMER FILMS PREPARED BY PEROXIDE CURING A WATER-BORNE FLUOROELASTOMER COATING | Lauren International, Inc. (US) | 2003-09-17 | — | — | EP | claimed |
| US-20020111417-A1 | Fluoroelastomer films prepared by peroxide curing a water-borne fluoroelastomer coating | LAUREN INTERNATIONAL, INC. | 2002-08-15 | — | — | US | claimed |
| WO-2002048251-A1 | FLUOROELASTOMER FILMS PREPARED BY PEROXIDE CURING A WATER-BORNE FLUOROELASTOMER COATING | LAUREN INTERNATIONAL, INC. (US) | 2002-06-20 | — | — | WO | claimed |
| CN-119322176-B | Biochip for simultaneously detecting multiple abundance markers and application thereof | 中国科学院杭州医学研究所 | 2025-03-25 | — | — | CN | disclosed |
| CN-119322176-A | Biochip for simultaneously detecting multiple abundance markers and application thereof | 中国科学院杭州医学研究所 | 2025-01-17 | — | — | CN | disclosed |
| US-6958141-B2 | Rhenium and technetium complexes containing a hypoxia-localizing moiety | BRACCO INTERNATIONAL B.V. (NL) | 2005-10-25 | — | — | US | disclosed |
| US-20040191174-A1 | Rhenium and technetium complexes containing a hypoxia-localizing moiety | BRACCO SUISSE SA (CH) | 2004-09-30 | — | — | US | disclosed |
| US-6699458-B2 | CELL MEMBRANE PERMEABILITIES GREATER THAN THAT OF SUCROSE | BRACCO INTERNATIONAL B.V. (NL) | 2004-03-02 | — | — | US | disclosed |
| US-20040010127-A1 | RHENIUM AND TECHNETIUM COMPLEXES CONTAINING A HYPOXIA-LOCALIZING MOIETY | BRACCO SUISSE SA (CH) | 2004-01-15 | — | — | US | disclosed |
| EP-1343837-A1 | FLUOROELASTOMER FILMS PREPARED BY PEROXIDE CURING A WATER-BORNE FLUOROELASTOMER COATING | Lauren International, Inc. (US) | 2003-09-17 | — | — | EP | disclosed |
| US-20020111417-A1 | Fluoroelastomer films prepared by peroxide curing a water-borne fluoroelastomer coating | LAUREN INTERNATIONAL, INC. | 2002-08-15 | — | — | US | disclosed |
| US-5688487-A | Diagnostic imaging methods using rhenium and technetium complexes containing a hypoxia-localizing moiety | BRACCO INTERNATIONAL B.V. (NL) | 1997-11-18 | — | — | US | disclosed |
| EP-0654025-A4 | METHOD OF PREPARING OPTICALLY PURE PRECURSORS OF PAROXETINE. | SEPRACOR INC (US) | 1995-10-11 | — | — | EP | disclosed |
| EP-0654025-A1 | METHOD OF PREPARING OPTICALLY PURE PRECURSORS OF PAROXETINE | SEPRACOR, INC. (US) | 1995-05-24 | — | — | EP | disclosed |
| EP-0417870-B1 | Chelates for complexation of radioactive isotopes, their metal complexes and their use in diagnosis and therapy | DIAGNOSTIKFORSCHUNG INST (DE) | 1994-07-20 | — | — | EP | disclosed |
| US-5302370-A | Form complexes with rhenium and technetium | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 1994-04-12 | — | — | US | disclosed |
| WO-1994003428-A1 | METHOD OF PREPARING OPTICALLY PURE PRECURSORS OF PAROXETINE | SEPRACOR, INC. (US) | 1994-02-17 | — | — | WO | disclosed |
| US-5258517-A | Method of preparing optically pure precursors of paroxetine | SEPRACOR, INC. (US) | 1993-11-02 | — | — | US | disclosed |
| EP-0417870-A2 | Chelates for complexation of radioactive isotopes, their metal complexes and their use in diagnosis and therapy | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 1991-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040191174-A1 | Rhenium and technetium complexes containing a hypoxia-localizing moiety | HIF1A, HIF1AN, SLC2A8 | GRIK1 2319/4885GRIK2 1781/4885CYP2C19 4764/4885 |
| US-20040010127-A1 | RHENIUM AND TECHNETIUM COMPLEXES CONTAINING A HYPOXIA-LOCALIZING MOIETY | HIF1A, HIF1AN, SLC2A8 | GRIK1 2319/4885GRIK2 1781/4885CYP2C19 4764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.