Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 10/20 | 0.76 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | RARB | P10826 | 3/20 | 0.64 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanoate SCHEMBL28099951 | 0.93 | PLA2G4B (0.68) | PLA2G4BTP53TSHRGAAL3MBTL1 | |
| Sebacic Acid SCHEMBL28178734 | 0.92 | TP53 (0.85) | PLA2G4BTP53TSHRRARB | |
| SCHEMBL11845832 | 0.91 | S1PR1 (0.67) | PLA2G4BTP53TSHRGAAL3MBTL1 | |
| SCHEMBL9075091 | 0.91 | THRA (0.68) | PLA2G4BTP53TSHRL3MBTL1RARB | |
| SCHEMBL2185966 | 0.91 | S1PR1 (0.67) | PLA2G4BTP53TSHRGAAL3MBTL1 | |
| SCHEMBL2185272 | 0.91 | S1PR1 (0.67) | PLA2G4BTP53TSHRGAAL3MBTL1 | |
| SCHEMBL9663932 | 0.91 | S1PR1 (0.67) | PLA2G4BTP53TSHRGAAL3MBTL1 | |
| SCHEMBL29089242 | 0.91 | PLA2G4B (0.68) | PLA2G4BTP53TSHRGAAL3MBTL1 | |
| SCHEMBL29141429 | 0.91 | PPARA (0.71) | PLA2G4BGAAL3MBTL1 | |
| SCHEMBL31448424 | 0.91 | PPARA (0.71) | PLA2G4BGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679801-A | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-10-21 | — | — | US | disclosed |
| US-5242945-A | Antiinflammatory | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-09-07 | — | — | US | disclosed |
| EP-0508690-A1 | Tetronic and thiotetronic acid derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-10-14 | — | — | EP | disclosed |