Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921602 | 0.71 | MEN1 (0.61) | MAPTABL1MEN1LMNAKMT2A | |
| SCHEMBL3532872 | 0.71 | MAPT (0.41) | MAPTABL1POLBMCOLN3KMT2A | |
| SCHEMBL6649136 | 0.70 | ABL1 (0.60) | MAPTABL1POLBMCOLN3MEN1 | |
| SCHEMBL14443210 | 0.69 | MAPT (0.62) | MAPTPOLBMEN1LMNAKMT2A | |
| SCHEMBL7643547 | 0.69 | ABL1 (0.55) | MAPTABL1POLBMCOLN3MEN1 | |
| SCHEMBL29110340 | 0.69 | POLB (0.48) | MAPTABL1POLBMCOLN3MEN1 | |
| SCHEMBL5499901 | 0.68 | ABL1 (0.54) | MAPTABL1MEN1LMNAKMT2A | |
| SCHEMBL31058534 | 0.68 | ALDH1A1 (0.58) | MAPTABL1POLBMEN1LMNA | |
| SCHEMBL11775995 | 0.68 | ALDH1A1 (0.58) | MAPTABL1POLBMEN1LMNA | |
| SCHEMBL27388946 | 0.67 | ABL1 (0.49) | MAPTABL1POLBMCOLN3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |