Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921812 | 1.00 | KDM4E (0.47) | KDM4EMAPTALDH1A1NPC1MAPK1 | |
| SCHEMBL8921801 | 1.00 | KDM4E (0.47) | KDM4EMAPTALDH1A1NPC1MAPK1 | |
| SCHEMBL8920123 | 0.80 | KDM4E (0.52) | KDM4EMAPTALDH1A1CYP1A2POLB | |
| SCHEMBL8920155 | 0.79 | KDM4E (0.54) | KDM4EMAPTALDH1A1CYP1A2POLB | |
| SCHEMBL8921443 | 0.78 | MAPT (0.67) | KDM4EMAPTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8920133 | 0.76 | KDM4E (0.51) | KDM4EMAPTALDH1A1CYP1A2POLB | |
| SCHEMBL8921390 | 0.76 | KDM4E (0.67) | KDM4EALDH1A1CYP1A2CYP3A4GRIN2D | |
| SCHEMBL7461224 | 0.76 | GRIN2D (0.53) | KDM4ECYP1A2POLBCYP3A4CYP2C9 | |
| SCHEMBL8923489 | 0.76 | KDM4E (0.50) | KDM4EMAPTALDH1A1CYP1A2POLB | |
| SCHEMBL8922324 | 0.76 | KDM4E (0.47) | KDM4EMAPTALDH1A1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |