Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56058 | 1.00 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL11501635 | 1.00 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL8558475 | 1.00 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL1415394 | 0.97 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL386067 | 0.97 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL11554992 | 0.94 | — | — | |
| SCHEMBL3789483 | 0.94 | — | — | |
| SCHEMBL8638311 | 0.94 | — | — | |
| SCHEMBL11501880 | 0.94 | — | — | |
| SCHEMBL6840832 | 0.91 | ALDH1A1 (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145874-A | Phospholipase inhibitor, hypoglycemic agent, antidiabetic, obesity | THE UPJOHN COMPANY (US) | 1992-09-08 | — | — | US | claimed |
| EP-0243449-A1 | CYCLIC HYDROCARBONS WITH AN AMINOALKYL SIDECHAIN | THE UPJOHN COMPANY (US) | 1987-11-04 | — | — | EP | claimed |
| WO-1987002367-A2 | CYCLIC HYDROCARBONS WITH AN AMINOALKYL SIDECHAIN | THE UPJOHN COMPANY (US) | 1987-04-23 | — | — | WO | claimed |
| CN-1809530-A | Haloalkyl containing compounds as cysteine protease inhibitors | AXYS PHARM INC (US) | 2006-07-26 | — | — | CN | disclosed |
| CN-1065277-C | Process for production of avermectins and cultures therefor | PFIZER (US) | 2001-05-02 | — | — | CN | disclosed |
| US-5621123-A | Cyclic hydrocarbons with an aminoalkyl sidechain | THE UPJOHN COMPANY (US) | 1997-04-15 | — | — | US | disclosed |
| US-5583015-A | CULTURING MUTANT STRAIN OF STREPTOMYCES AVERMITILIS LACKING BRANCHED CHAIN AMINO ACID TRANSAMINASE AND/OR 2-OXO ACID DEHYDROGENASE ACTIVITY UNDER AEROBIC CONDITIONS IN AQUEOUS NUTRIENT MEDIUM CONTAINING SPECIFIED ACID OR PRECURSOR | PFIZER INC. (US) | 1996-12-10 | — | — | US | disclosed |
| US-5373095-A | Steroid compounds | THE UPJOHN COMPANY (US) | 1994-12-13 | — | — | US | disclosed |
| US-5334712-A | Estrane or androstane pyridinyl alkyl or alkylphenyl amine steroids for antidiabetes and obesity | THE UPJOHN COMPANY (US) | 1994-08-02 | — | — | US | disclosed |
| US-5274089-A | A estra-1,3,5(10)-triene derivative | THE UPJOHN COMPANY (US) | 1993-12-28 | — | — | US | disclosed |
| US-5196542-A | Phospholipase A2 inhibitors | THE UPJOHN COMPANY (US) | 1993-03-23 | — | — | US | disclosed |
| US-5187299-A | Phospholipase inhibitors; treating diabetes, obesity | THE UPJOHN COMPANY (US) | 1993-02-16 | — | — | US | disclosed |
| US-5145874-A | Phospholipase inhibitor, hypoglycemic agent, antidiabetic, obesity | THE UPJOHN COMPANY (US) | 1992-09-08 | — | — | US | disclosed |
| US-4917826-A | TREATING DIABETES AND OBESITY | THE UPJOHN COMPANY (US) | 1990-04-17 | — | — | US | disclosed |
| CN-88100373-A | Avermectins and production method of culture bacteria thereof | — | 1988-08-31 | — | — | CN | disclosed |