Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | GLB1 | P16278 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10051725 | 0.89 | PI4KA (0.41) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL24686932 | 0.89 | PI4KA (0.41) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL12355482 | 0.80 | CA2 (0.35) | ALDH1A1CA2CA1CA9GLB1 | |
| SCHEMBL13747442 | 0.80 | PI4KA (0.40) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL803317 | 0.80 | PI4KA (0.40) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL9805595 | 0.80 | PI4KA (0.40) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL4760678 | 0.80 | PI4KA (0.40) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL12347904 | 0.80 | CA2 (0.35) | ALDH1A1CA2CA1CA9GLB1 | |
| SCHEMBL20844612 | 0.80 | PI4KA (0.40) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL29546906 | 0.80 | CA2 (0.35) | ALDH1A1CA2CA1CA9GLB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703224-A | Antiviral c-nucleoside derivatives | NIPPON SHINYAKU CO. LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0733630-A1 | NUCLEOSIDE DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-09-25 | — | — | EP | disclosed |