Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922105 | 0.81 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL19253305 | 0.78 | ALDH1A1 (0.54) | ALDH1A1 | |
| SCHEMBL184348 | 0.78 | ALDH1A1 (0.54) | ALDH1A1 | |
| SCHEMBL11066714 | 0.78 | ALDH1A1 (0.54) | ALDH1A1 | |
| SCHEMBL19253228 | 0.78 | ALDH1A1 (0.54) | ALDH1A1 | |
| SCHEMBL8931389 | 0.76 | — | — | |
| SCHEMBL2286052 | 0.76 | — | — | |
| SCHEMBL18740462 | 0.76 | — | — | |
| SCHEMBL15014301 | 0.74 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL3774067 | 0.74 | ALDH1A1 (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145874-A | Phospholipase inhibitor, hypoglycemic agent, antidiabetic, obesity | THE UPJOHN COMPANY (US) | 1992-09-08 | — | — | US | claimed |
| EP-0243449-A1 | CYCLIC HYDROCARBONS WITH AN AMINOALKYL SIDECHAIN | THE UPJOHN COMPANY (US) | 1987-11-04 | — | — | EP | claimed |
| WO-1987002367-A2 | CYCLIC HYDROCARBONS WITH AN AMINOALKYL SIDECHAIN | THE UPJOHN COMPANY (US) | 1987-04-23 | — | — | WO | claimed |
| US-5621123-A | Cyclic hydrocarbons with an aminoalkyl sidechain | THE UPJOHN COMPANY (US) | 1997-04-15 | — | — | US | disclosed |
| US-5373095-A | Steroid compounds | THE UPJOHN COMPANY (US) | 1994-12-13 | — | — | US | disclosed |
| US-5334712-A | Estrane or androstane pyridinyl alkyl or alkylphenyl amine steroids for antidiabetes and obesity | THE UPJOHN COMPANY (US) | 1994-08-02 | — | — | US | disclosed |
| US-5274089-A | A estra-1,3,5(10)-triene derivative | THE UPJOHN COMPANY (US) | 1993-12-28 | — | — | US | disclosed |
| US-5196542-A | Phospholipase A2 inhibitors | THE UPJOHN COMPANY (US) | 1993-03-23 | — | — | US | disclosed |
| US-5187299-A | Phospholipase inhibitors; treating diabetes, obesity | THE UPJOHN COMPANY (US) | 1993-02-16 | — | — | US | disclosed |
| US-5145874-A | Phospholipase inhibitor, hypoglycemic agent, antidiabetic, obesity | THE UPJOHN COMPANY (US) | 1992-09-08 | — | — | US | disclosed |
| US-4917826-A | TREATING DIABETES AND OBESITY | THE UPJOHN COMPANY (US) | 1990-04-17 | — | — | US | disclosed |