Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | DDO | Q99489 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20500079 | 0.82 | HCAR2 (0.52) | HCAR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2115989 | 0.82 | HCAR2 (0.52) | HCAR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL30281262 | 0.82 | HCAR2 (0.52) | HCAR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL31064091 | 0.82 | HCAR2 (0.52) | HCAR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL51830 | 0.79 | HCAR2 (0.70) | HCAR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23012143 | 0.79 | HCAR2 (0.53) | HCAR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL26680771 | 0.77 | NPC1 (0.51) | HCAR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL834425 | 0.77 | MAPT (0.58) | HCAR2ALDH1A1KDM4EMEN1KMT2A | |
| Fluoride SCHEMBL21331909 | 0.77 | HCAR2 (0.67) | HCAR2ALDH1A1KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7124062 | 0.77 | HCAR2 (0.67) | HCAR2ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |