Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.50 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | DDO | Q99489 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.52 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7661020 | 1.00 | HCAR2 (0.67) | HCAR2ALDH1A1KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1117746 | 1.00 | HCAR2 (0.67) | HCAR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL51830 | 0.97 | HCAR2 (0.70) | HCAR2ALDH1A1KDM4EMEN1KMT2A | |
| Bromide SCHEMBL21332093 | 0.94 | HCAR2 (0.67) | HCAR2ALDH1A1KDM4EMEN1KMT2A | |
| Fluoride SCHEMBL21331909 | 0.94 | HCAR2 (0.67) | HCAR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL19987838 | 0.94 | HCAR2 (0.67) | HCAR2ALDH1A1KDM4EMEN1KMT2A | |
| Acetic Acid SCHEMBL28240357 | 0.87 | HCAR2 (0.65) | HCAR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1242033 | 0.85 | MKNK1 (0.65) | HCAR2ALDH1A1KDM4EMEN1KMT2A | |
| Fumaric Acid SCHEMBL17350555 | 0.85 | HCAR2 (0.57) | HCAR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL31064103 | 0.85 | HCAR2 (0.63) | HCAR2ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114983931-A | Preparation method and application of injection type pyridine amide derivative micromolecule in-situ gel preparation | 赣南师范大学 | 2022-09-02 | — | — | CN | claimed |
| US-20250376543-A1 | HYALURONIC ACID-COLLAGEN COPOLYMER COMPOSITIONS AND MEDICAL APPLICATIONS THEREOF | SHANGHAI QISHENG BIOLOGICAL PREPARATION CO LTD (CN) | 2025-12-11 | — | — | US | disclosed |
| US-12304974-B2 | Hyaluronic acid-collagen copolymer compositions and medical applications thereof | SHANGHAI QISHENG BIOLOGICAL PREPARATION CO., LTD. (CN) | 2025-05-20 | — | — | US | disclosed |
| US-20240252446-A1 | DERIVATIZED COLLAGEN-HYALURONIC ACID BASED IMPLANTS FOR SUSTAINED DELIVERY OF OPHTHALMIC DRUGS | SUSTAINED DRUG DELIVERY LLC | 2024-08-01 | — | — | US | disclosed |
| US-20230203207-A1 | HYALURONIC ACID-COLLAGEN COPOLYMER COMPOSITIONS AND MEDICAL APPLICATIONS THEREOF | SHANGHAI QISHENG BIOLOGICAL PREPARATION CO., LTD. (CN) | 2023-06-29 | — | — | US | disclosed |
| CN-114983931-A | Preparation method and application of injection type pyridine amide derivative micromolecule in-situ gel preparation | 赣南师范大学 | 2022-09-02 | — | — | CN | disclosed |
| EP-3512905-B1 | METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) | BASF SE (DE) | 2022-08-24 | — | — | EP | disclosed |
| US-10941252-B2 | Silicone copolymers, methods of making, and articles | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2021-03-09 | — | — | US | disclosed |
| EP-3762447-A1 | METHOD FOR PRODUCING FIBRES, FILMS AND MOULDED BODIES OF A POLYBENZAZOLE POLYMER (P) | BASF SE (DE) | 2021-01-13 | — | — | EP | disclosed |
| WO-2019170529-A1 | METHOD FOR PRODUCING FIBRES, FILMS AND MOULDED BODIES OF A POLYBENZAZOLE POLYMER (P) | BASF SE (DE) | 2019-09-12 | — | — | WO | disclosed |
| WO-1992021674-A1 | CYCLIC ALKYLIDENE SUBSTITUTED PYRIDINE HERBICIDES | MONSANTO COMPANY (US) | 1992-12-10 | — | — | WO | disclosed |
| US-5156670-A | Low soil mobility | MONSANTO COMPANY (US) | 1992-10-20 | — | — | US | disclosed |
| US-4883864-A | COUPLED AND FREE AMINE GROUPS CAPPED WITH UREA OR AMIDE GROUPS, EYE SURGERY | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| US-4851513-A | Viscoelastic collagen solution for opthalmic use and method of preparation | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-07-25 | — | — | US | disclosed |
| US-4803151-A | Photographic material for the silver dye bleach process comprising an AZO dye, capable of laking, in gelatine | CIBA-GEIGY AG (CH) | 1989-02-07 | — | — | US | disclosed |
| US-4713446-A | COLLAGEN COUPLED TO CARBONYL OR SULFONYL GROUPS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-12-15 | — | — | US | disclosed |
| EP-0214853-A2 | Viscoelastic collagen solution for ophthalmic use and method of preparation | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-03-18 | — | — | EP | disclosed |
| US-4118232-A | Photographic material containing sulphonic acid group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1978-10-03 | — | — | US | disclosed |
| US-4051123-A | Sulfonic-acid-group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1977-09-27 | — | — | US | disclosed |
| US-3931142-A | Heterocyclic containing disazo compounds | CIBA-GEIGY AG (CH) | 1976-01-06 | — | — | US | disclosed |