Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.50 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037377 | 0.79 | GLA (0.56) | ALDH1A1GLATDP1MAPTHDAC3 | |
| SCHEMBL3127156 | 0.78 | TDP1 (0.64) | ALDH1A1GLATDP1MAPTHDAC3 | |
| SCHEMBL10620508 | 0.78 | TDP1 (0.64) | ALDH1A1GLATDP1MAPTHDAC3 | |
| SCHEMBL221211 | 0.78 | TDP1 (0.64) | ALDH1A1GLATDP1MAPTHDAC3 | |
| E-Methyl Cinnamate SCHEMBL28251050 | 0.77 | CA12 (0.65) | ALDH1A1GLATDP1MAPTHDAC3 | |
| E-Methyl Cinnamate SCHEMBL28251051 | 0.77 | CA12 (0.65) | ALDH1A1GLATDP1MAPTHDAC3 | |
| E-Methyl Cinnamate SCHEMBL901224 | 0.76 | CA12 (0.69) | ALDH1A1GLATDP1MAPTHDAC3 | |
| E-Methyl Cinnamate SCHEMBL2425288 | 0.76 | CA12 (0.69) | ALDH1A1GLATDP1MAPTHDAC3 | |
| E-Methyl Cinnamate SCHEMBL101530 | 0.76 | CA12 (0.69) | ALDH1A1GLATDP1MAPTHDAC3 | |
| E-Methyl Cinnamate SCHEMBL112062 | 0.76 | CA12 (0.69) | ALDH1A1GLATDP1MAPTHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802897-A1 | NOVEL COMPOUNDS | Smithkline Beecham S.p.A. (IT) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996021638-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM S.P.A. (IT) | 1996-07-18 | — | — | WO | disclosed |