Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL358474 | 0.79 | MEN1 (0.59) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL6829825 | 0.77 | TDP1 (0.49) | TSHRLTA4HEPHX2KMT2AMEN1 | |
| SCHEMBL20710698 | 0.77 | LTA4H (0.52) | TSHRLTA4HEPHX2KMT2AMEN1 | |
| SCHEMBL31482559 | 0.76 | MEN1 (0.49) | LTA4HEPHX2KMT2AMEN1CA12 | |
| Triphenylphosphine Oxide SCHEMBL8846399 | 0.76 | MEN1 (0.60) | LTA4HEPHX2KMT2AMEN1CA12 | |
| SCHEMBL2960872 | 0.75 | CYP2C19 (0.78) | CYP2C19TSHRCNR2NR3C1KMT2A | |
| SCHEMBL6794322 | 0.75 | LTA4H (0.67) | CYP2C19LTA4HEPHX2KMT2AMEN1 | |
| SCHEMBL13541379 | 0.75 | HRH3 (0.47) | TSHRLTA4HEPHX2KMT2AMEN1 | |
| Phosphoric Acid SCHEMBL28091785 | 0.74 | MEN1 (0.58) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL7144174 | 0.74 | NPY1R (0.41) | LTA4HEPHX2KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670493-A | ANGIOGENESIS INHIBITORS | ADIR ET COMPAGNIE (FR) | 1997-09-23 | — | — | US | disclosed |