Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12326843 | 0.75 | MEN1 (0.36) | MEN1POLBKMT2A | |
| SCHEMBL3189861 | 0.75 | TSHR (0.38) | MEN1KMT2A | |
| SCHEMBL15966760 | 0.75 | BCHE (0.41) | MEN1POLBKMT2A | |
| SCHEMBL9831993 | 0.73 | MEN1 (0.37) | MEN1POLBKMT2A | |
| SCHEMBL5892580 | 0.73 | TSHR (0.44) | MEN1POLBKMT2A | |
| SCHEMBL2494291 | 0.73 | MEN1 (0.32) | MEN1POLBKMT2A | |
| SCHEMBL737146 | 0.73 | KCNH2 (0.35) | — | |
| SCHEMBL5892346 | 0.73 | TSHR (0.44) | MEN1POLBKMT2A | |
| SCHEMBL347715 | 0.72 | HRH3 (0.33) | MEN1POLBKMT2A | |
| SCHEMBL8861569 | 0.71 | TSHR (0.33) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |