SCHEMBL8922333

SCHEMBL8922333

O=C(CCC1CCNCC1)c1ccc(Nc2ncnc3c2CCC3)cc1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
KMT2A Q03164 1/20 0.38
ITGB3 P05106 4/20 0.37
ITGA2B P08514 4/20 0.37
SUV39H1 O43463 1/20 0.36
PRMT1 Q99873 1/20 0.36
SMYD3 Q9H7B4 1/20 0.36
PDE4B Q07343 2/20 0.36
TRPV1 Q8NER1 4/20 0.35
AURKA O14965 1/20 0.34
RPS6KB1 P23443 1/20 0.34
ACHE P22303 1/20 0.34
FAAH O00519 1/20 0.34
RET P07949 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8133355 0.99 TSHR (0.38) TSHRKMT2AITGB3ITGA2BSUV39H1
SCHEMBL8125432 0.90 TSHR (0.39) TSHRSUV39H1PRMT1SMYD3PDE4B
Hydrochloric Acid SCHEMBL8129126 0.89 TSHR (0.39) TSHRSUV39H1PRMT1SMYD3PDE4B
SCHEMBL8128731 0.82 ACHE (0.58) ACHE
Hydrochloric Acid SCHEMBL8130199 0.81 ACHE (0.58) ACHE
SCHEMBL8134936 0.80 ACHE (0.51) ACHE
SCHEMBL8128236 0.80 ACHE (0.58) ACHE
SCHEMBL8922063 0.79 ACHE (0.41) KMT2ATRPV1ACHE
SCHEMBL8133724 0.79 ACHE (0.43) ACHE
Hydrochloric Acid SCHEMBL8135732 0.78 ACHE (0.41) KMT2ATRPV1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5610303-A MONOAMIDE OXIDASE INHIBITORS UBE INDUSTRIES, LTD. (JP) 1997-03-11 US disclosed