Propane

Propane

SCHEMBL8922359

CCC.OCC(O)COCC1CO1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.47
SMN1; SMN2 Q16637 1/20 0.44
TDP1 Q9NUW8 1/20 0.42
USP2 O75604 1/20 0.42
TSHR P16473 2/20 0.41
MAPK1 P28482 1/20 0.41
CYP2D6 P10635 1/20 0.32
KDM4E B2RXH2 2/20 0.32
CYP1A2 P05177 1/20 0.32
DUSP3 P51452 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40586 0.94 TSHR (0.45) ALDH1A1SMN1; SMN2TDP1USP2TSHR
Ether SCHEMBL21829109 0.93 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2TDP1USP2TSHR
SCHEMBL16134389 0.92 TSHR (0.43) ALDH1A1SMN1; SMN2TDP1USP2TSHR
Methane SCHEMBL28850574 0.92 TSHR (0.43) ALDH1A1SMN1; SMN2TDP1USP2TSHR
Benzene SCHEMBL28184515 0.89 TSHR (0.41) ALDH1A1SMN1; SMN2TDP1USP2TSHR
SCHEMBL27870592 0.89 TSHR (0.43) ALDH1A1SMN1; SMN2TDP1USP2TSHR
SCHEMBL8931133 0.87 TSHR (0.39) ALDH1A1SMN1; SMN2TDP1USP2TSHR
SCHEMBL4282114 0.85 TSHR (0.50) ALDH1A1SMN1; SMN2TDP1USP2TSHR
SCHEMBL28401907 0.85 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL16134384 0.84 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2TDP1USP2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0585157-B1 Amphiphilic fluorinated polyglycerol sulphur compounds cosmetic or pharmaceutical compositions containing them, process for preparation and formed vesicles OREAL (FR) 1996-03-20 EP claimed
US-5591449-A Vesicles, and cosmetic or pharmaceutical compositions containing vesicles, bounded by one or more lamellae composed of a lipid phase containing fluorine-containing, polyglycerolated amphilic sulphur compounds L'OREAL (FR) 1997-01-07 US disclosed
US-5459165-A Applying to skin or mucous membranes L'OREAL (FR) 1995-10-17 US disclosed