SCHEMBL8922674

SCHEMBL8922674

CCCC(c1cc(O)cc(C(C)(C)C)c1O)c1cc(O)cc(C(C)(C)C)c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 6/20 0.57
CYP2C19 P33261 5/20 0.57
ALOX15 P16050 5/20 0.57
TP53 P04637 2/20 0.57
CYP2D6 P10635 1/20 0.57
CYP1A2 P05177 4/20 0.49
TSHR P16473 3/20 0.49
CYP3A4 P08684 2/20 0.49
CA2 P00918 3/20 0.41
CA1 P00915 2/20 0.41
ALDH1A1 P00352 6/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
TYR P14679 2/20 0.39
POLB P06746 1/20 0.39
GLRA3 O75311 1/20 0.39
GLRB P48167 1/20 0.39
HSPA5 P11021 2/20 0.39
LMNA P02545 4/20 0.37
NR1I2 O75469 1/20 0.37
MIF P14174 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4594355 0.86 CYP2C19 (0.66) CYP2C9CYP2C19ALOX15TP53CYP2D6
SCHEMBL70420 0.86 CYP2C9 (0.58) CYP2C9CYP2C19ALOX15TP53CYP2D6
SCHEMBL551770 0.85 HSPA5 (0.54) CYP2C9CYP2C19ALOX15TP53CYP2D6
SCHEMBL23784442 0.83 CYP2C9 (0.43) CYP2C9CYP2C19ALOX15TP53CYP2D6
SCHEMBL14432017 0.81 CYP2C9 (0.52) CYP2C9CYP2C19ALOX15TP53CYP2D6
SCHEMBL14493481 0.81 CYP2C9 (0.56) CYP2C9CYP2C19ALOX15TP53CYP2D6
SCHEMBL2017743 0.79 CYP2C9 (0.62) CYP2C9CYP2C19ALOX15TP53CYP2D6
SCHEMBL14002957 0.79 CYP2C9 (0.47) CYP2C9CYP2C19ALOX15TP53CYP2D6
SCHEMBL20602843 0.78 CYP2C9 (0.56) CYP2C9CYP2C19ALOX15TP53CYP2D6
SCHEMBL223426 0.78 ALOX15 (0.51) CYP2C9CYP2C19ALOX15TP53CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0330504-B1 Photosensitive material and image forming method CANON KK (JP) 1996-05-22 EP claimed
US-5663032-A NAPHTHOL DERIVATIVE REDUCING AGENT CANON KABUSHIKI KAISHA (JP) 1997-09-02 US disclosed
EP-0332455-B1 Photosensitive material and image forming method CANON KK (JP) 1996-06-05 EP disclosed
EP-0330504-B1 Photosensitive material and image forming method CANON KK (JP) 1996-05-22 EP disclosed
EP-0653680-A2 Photosensitive composition, photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1995-05-17 EP disclosed
US-5415974-A Silver halide, organic silver salt, polymerizable compound, heat-diffusing dye CANON KABUSHIKI KAISHA (JP) 1995-05-16 US disclosed
US-5260164-A Silver halide, organic silver salt, cyclic reducing agent, the above compounds adapted to provide imagewise oxidized product of reducing agent upon imagewise exposure and heat development, polymer precursor, photopolymerization initiator CANON KABUSHIKI KAISHA (JP) 1993-11-09 US disclosed
US-5064744-A Heat, photopolymerization, silver halide contrast CANON KABUSHIKI KAISHA (JP) 1991-11-12 US disclosed
US-5041369-A Silver Halide, Silver Salt, Reducing Agent, Metal or Organic Dye CANON KABUSHIKI KAISHA (JP) 1991-08-20 US disclosed
EP-0360014-A1 Photosensitive material and image forming method using same CANON KABUSHIKI KAISHA (JP) 1990-03-28 EP disclosed
EP-0330504-A2 Photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1989-08-30 EP disclosed
EP-0326424-A2 Photosensitive composition, photosensitive material, and image forming method CANON KABUSHIKI KAISHA (JP) 1989-08-02 EP disclosed