Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052944 | 0.97 | HDAC8 (0.33) | HDAC8 | |
| Hydrochloric Acid SCHEMBL8919518 | 0.95 | HDAC8 (0.32) | HDAC8 | |
| SCHEMBL11880213 | 0.73 | HDAC8 (0.31) | HDAC8 | |
| Hydrochloric Acid SCHEMBL27618275 | 0.70 | — | — | |
| SCHEMBL1695333 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL9627054 | 0.70 | — | — | |
| SCHEMBL4701356 | 0.67 | CYP2C19 (0.34) | — | |
| SCHEMBL10697550 | 0.67 | — | — | |
| SCHEMBL8827254 | 0.67 | — | — | |
| SCHEMBL18035806 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686619-A | CHLORINATION OF HYDROXYALKYLPYRIDINIUM CHLORIDE WITH THIONYL CHLORIDE | CYTEC TECHNOLOGY CORP. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5521316-A | FREE-FLOWING DUSTLESS POWDER FOR AGRICULTURE | CYTEC TECHNOLOGY CORP. (US) | 1996-05-28 | — | — | US | disclosed |