Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.62 |
| ▸ | HTR2A | P28223 | 9/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4824572 | 0.86 | HRH1 (0.55) | SLC6A4HTR2ASLC6A2SLC6A3HRH1 | |
| SCHEMBL11240000 | 0.85 | SLC6A4 (0.48) | SLC6A4HTR2ASLC6A2SLC6A3KCNH2 | |
| SCHEMBL11339338 | 0.83 | SLC6A4 (0.66) | SLC6A4HTR2ASLC6A2SLC6A3HRH1 | |
| SCHEMBL11578002 | 0.83 | SLC6A4 (0.62) | SLC6A4HTR2ASLC6A2SLC6A3MAPT | |
| SCHEMBL10958172 | 0.83 | SLC6A4 (0.58) | SLC6A4HTR2ASLC6A2SLC6A3MAPT | |
| SCHEMBL11122829 | 0.82 | SLC6A4 (0.50) | SLC6A4HTR2ASLC6A2SLC6A3MAPT | |
| SCHEMBL7770746 | 0.79 | SLC6A4 (0.56) | SLC6A4HTR2ASLC6A2SLC6A3KCNH2 | |
| SCHEMBL11702925 | 0.79 | SLC6A4 (0.65) | SLC6A4HTR2ASLC6A2SLC6A3MAPT | |
| SCHEMBL12929642 | 0.77 | SLC6A4 (0.68) | SLC6A4HTR2ASLC6A2SLC6A3MAPT | |
| SCHEMBL4639195 | 0.77 | SLC6A4 (0.63) | SLC6A4HTR2ASLC6A2SLC6A3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650539-A | ALKYLATION, ESTERIFICATION, DEESTERIFICATION, AMIDATION, FUNGICIDES | SHIONOGI & CO., LTD. (JP) | 1997-07-22 | — | — | US | disclosed |
| US-5488159-A | AMIDATION, METHYLATION, FUNGICIDE | SHIONOGI & CO., LTD. (JP) | 1996-01-30 | — | — | US | disclosed |
| US-5380913-A | E-Isomers of 2-methoxyimino-N-methyl-2-phenoxyphenylacetamides and alkyl 2-methoxyimino-2-phenoxyphenylacetates produced by reacting Z-isomers with hydrogen chloride or hydrochloric, sulfuric or toluenesulfonic acid in methyl, ethyl or butyl alc | SHIONOGI & CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| EP-0468775-B1 | Process for producing methoxyiminoacetamide compounds and intermediates | SHIONOGI & CO (JP) | 1994-12-14 | — | — | EP | disclosed |
| EP-0606924-A1 | Process for producing E-isomers of methoxyminoacetamide compounds | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1994-07-20 | — | — | EP | disclosed |
| EP-0605392-A1 | Process for producing methoxyminoacetamide compounds | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1994-07-06 | — | — | EP | disclosed |
| US-5183921-A | Agricultural fungicides | SHIONOGI & CO., LTD. (JP) | 1993-02-02 | — | — | US | disclosed |
| EP-0468775-A1 | Process for producing methoxyiminoacetamide compounds and intermediates | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1992-01-29 | — | — | EP | disclosed |
| EP-0016261-B1 | SPIRO(DIBENZ(B,F)OXEPIN-PIPERIDINES) AND METHODS OF PREPARING SAME | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-12-29 | — | — | EP | disclosed |
| EP-0016261-A1 | Spiro(dibenz(b,f)oxepin-piperidines) and methods of preparing same | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-10-01 | — | — | EP | disclosed |
| US-4198417-A | ANALGESICS, ANTIDEPRESSANTS, ANTICONVULSANTS | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |
| US-4198418-A | ANALGESICS, TRANQUILIZERS, ANTICONVULSANTS | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |