Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.50 |
| ▸ | HTR2A | P28223 | 6/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11173106 | 0.87 | MEN1 (0.44) | SLC6A4HTR2ASLC6A2SLC6A3POLB | |
| SCHEMBL11124064 | 0.86 | SLC6A4 (0.51) | SLC6A4HTR2ASLC6A2SLC6A3MAPT | |
| SCHEMBL8922734 | 0.82 | SLC6A4 (0.62) | SLC6A4HTR2ASLC6A2SLC6A3MAPT | |
| SCHEMBL11125167 | 0.82 | SLC6A2 (0.47) | SLC6A4SLC6A2SLC6A3MAPTKCNH2 | |
| SCHEMBL11123672 | 0.81 | SLC6A4 (0.50) | SLC6A4HTR2ASLC6A2SLC6A3MAPT | |
| SCHEMBL4160051 | 0.80 | SMN1; SMN2 (0.46) | POLBGAAMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL14396317 | 0.80 | SLC6A4 (0.49) | SLC6A4HTR2ASLC6A2SLC6A3KCNH2 | |
| SCHEMBL11120686 | 0.80 | ALDH1A1 (0.42) | SLC6A4SLC6A2SLC6A3KCNH2POLB | |
| SCHEMBL11118768 | 0.77 | AR (0.47) | SLC6A4SLC6A2SLC6A3POLBNPC1 | |
| SCHEMBL11118737 | 0.77 | CHRM1 (0.48) | SLC6A4HTR2ASLC6A2SLC6A3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033614-B1 | PHENYLALKANOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-06 | — | — | EP | disclosed |
| US-4367238-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1983-01-04 | — | — | US | disclosed |
| EP-0033614-A1 | Phenylalkanoic acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-08-12 | — | — | EP | disclosed |