Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR1 | Q9GZQ6 | 6/20 | 0.46 |
| ▸ | NPFFR2 | Q9Y5X5 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7491453 | 1.00 | NPFFR1 (0.46) | NPFFR1NPFFR2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL7499070 | 1.00 | NPFFR1 (0.46) | NPFFR1NPFFR2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL7496985 | 0.87 | OPRM1 (0.41) | ACHE | |
| SCHEMBL7497718 | 0.83 | DRD4 (0.40) | NPFFR1NPFFR2ACHESIGMAR1 | |
| SCHEMBL7516286 | 0.81 | NPFFR1 (0.53) | NPFFR1NPFFR2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL7498641 | 0.81 | UTS2R (0.37) | ALDH1A1KMT2ASYK | |
| SCHEMBL9178875 | 0.81 | NPFFR1 (0.50) | NPFFR1NPFFR2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL7495543 | 0.80 | KDM4E (0.41) | ACHEBCHE | |
| SCHEMBL5463318 | 0.79 | NPFFR1 (0.52) | NPFFR1NPFFR2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL7492595 | 0.78 | OPRL1 (0.38) | ACHEBCHESIGMAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5621105-A | REACTING HALO-SUBSTITUTED QUINOLONECARBOXYLIC ACID OR NAPHTHYRIDONECARBOXYLIC ACID WITH 1-AMINOMETHYL-2-OXA-7-AZABICYCLO/3.3.0/OCTANE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |
| US-5574161-A | GRAMPOSITIVE BACTERICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-12 | — | — | US | disclosed |
| EP-0589318-B1 | Antibacterial 7-(aminomethyl-oxa-7-azabicyclo(3.3.0)oct-7-yl)quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1995-11-15 | — | — | EP | disclosed |
| US-5395944-A | Bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-03-07 | — | — | US | disclosed |
| EP-0589318-A2 | Antibacterial 7-(aminomethyl-oxa-7-azabicyclo(3.3.0)oct-7-yl)quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1994-03-30 | — | — | EP | disclosed |