SCHEMBL8922798

SCHEMBL8922798

CCCCCCCC/C=C\CCCCCCCCc1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.59
EPHX2 P34913 3/20 0.57
PPARA Q07869 2/20 0.57
FAAH O00519 2/20 0.55
PPARG P37231 1/20 0.53
CNR1 P21554 1/20 0.52
CNR2 P34972 1/20 0.52
SIGMAR1 Q99720 1/20 0.51
HTR2A P28223 1/20 0.51
KDM4E B2RXH2 2/20 0.50
MMP2 P08253 2/20 0.50
HSD17B10 Q99714 2/20 0.50
ESR1 P03372 2/20 0.50
ADRA2A P08913 2/20 0.50
ADORA3 P0DMS8 2/20 0.50
TACR2 P21452 2/20 0.50
SLC6A2 P23975 2/20 0.50
SLC6A4 P31645 2/20 0.50
SLC6A3 Q01959 2/20 0.50
F7 P08709 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10325657 1.00 KCNH2 (0.59) KCNH2EPHX2PPARAFAAHPPARG
SCHEMBL28977373 1.00 KCNH2 (0.59) KCNH2EPHX2PPARAFAAHPPARG
SCHEMBL8922816 1.00 KCNH2 (0.59) KCNH2EPHX2PPARAFAAHPPARG
SCHEMBL9529110 0.96 EPHX2 (0.62) KCNH2EPHX2PPARAFAAHPPARG
SCHEMBL19031854 0.94 EPHX2 (0.55) KCNH2EPHX2PPARAFAAHPPARG
SCHEMBL19031853 0.94 EPHX2 (0.55) KCNH2EPHX2PPARAFAAHPPARG
SCHEMBL19031842 0.92 EPHX2 (0.57) KCNH2EPHX2PPARAFAAHCNR1
SCHEMBL19031841 0.92 EPHX2 (0.57) KCNH2EPHX2PPARAFAAHCNR1
SCHEMBL22468798 0.92 EPHX2 (0.57) KCNH2EPHX2PPARAFAAHCNR1
SCHEMBL19031849 0.90 EPHX2 (0.55) KCNH2EPHX2PPARAFAAHCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5646098-A Carbonyl containing compounds and their derivatives as multi-functional fuel and lube additives EXXON CHEMICAL PATENTS INC (US) 1997-07-08 US disclosed
US-5550241-A Adducts of cyclic carbonyl monomers and substituted alkens EXXON RESEARCH AND ENGINEERING COMPANY (US) 1996-08-27 US disclosed
US-4498998-A Stabilization of hydrocracked oils against UV-light degradation with certain dihydroxy components ATLANTIC RICHFIELD COMPANY (US) 1985-02-12 US disclosed
EP-0040516-B1 STABILIZATION OF HYDROCRACKED OILS WITH CERTAIN DIHYDROXY DIPHENYL COMPONENTS ATLANTIC RICHFIELD COMPANY (US) 1984-07-04 EP disclosed
US-4427563-A LUBRICATING OIL ADDITIVES ATLANTIC RICHFIELD COMPANY (US) 1984-01-24 US disclosed
EP-0040516-A1 Stabilization of hydrocracked oils with certain dihydroxy diphenyl components ATLANTIC RICHFIELD COMPANY (US) 1981-11-25 EP disclosed