Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.62 |
| ▸ | FAAH | O00519 | 2/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
| ▸ | F7 | P08709 | 1/20 | 0.52 |
| ▸ | F3 | P13726 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922798 | 0.96 | KCNH2 (0.59) | EPHX2FAAHCNR1CNR2KCNH2 | |
| SCHEMBL28977373 | 0.96 | KCNH2 (0.59) | EPHX2FAAHCNR1CNR2KCNH2 | |
| SCHEMBL8922816 | 0.96 | KCNH2 (0.59) | EPHX2FAAHCNR1CNR2KCNH2 | |
| SCHEMBL10325657 | 0.96 | KCNH2 (0.59) | EPHX2FAAHCNR1CNR2KCNH2 | |
| SCHEMBL19031854 | 0.91 | EPHX2 (0.55) | EPHX2FAAHCNR1CNR2KCNH2 | |
| SCHEMBL19031853 | 0.91 | EPHX2 (0.55) | EPHX2FAAHCNR1CNR2KCNH2 | |
| SCHEMBL19031842 | 0.89 | EPHX2 (0.57) | EPHX2FAAHCNR1CNR2KCNH2 | |
| SCHEMBL19031841 | 0.89 | EPHX2 (0.57) | EPHX2FAAHCNR1CNR2KCNH2 | |
| SCHEMBL22468798 | 0.89 | EPHX2 (0.57) | EPHX2FAAHCNR1CNR2KCNH2 | |
| SCHEMBL19031849 | 0.87 | EPHX2 (0.55) | EPHX2FAAHCNR1CNR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253370-B1 | 1,3,5-Trithian derivatives | NIHON NOHYAKU CO LTD (JP) | 1993-11-18 | — | — | EP | disclosed |
| US-5045562-A | Antilipemic and antiarteriosclerotic | NIHON NOHYAKU CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| US-4816475-A | ANTIARTERIOSCLEROTIC OR ANTIHYPERLIPEMIC AGENTS | NIHON NOHYAKU CO. LTD. (JP) | 1989-03-28 | — | — | US | disclosed |