Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 11/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922931 | 1.00 | APP (0.39) | APPCYP19A1NQO2MAOAMAOB | |
| SCHEMBL14244323 | 0.83 | CA12 (0.50) | APPCYP19A1NQO2MAOAMAOB | |
| SCHEMBL8662084 | 0.83 | MAOB (0.42) | MAOBTDP1CYP1A2NPSR1NR1I2 | |
| SCHEMBL4821198 | 0.83 | NPSR1 (0.36) | TSHRTDP1LMNANPSR1NR1I2 | |
| SCHEMBL4821195 | 0.83 | NPSR1 (0.36) | TSHRTDP1LMNANPSR1NR1I2 | |
| SCHEMBL8662087 | 0.83 | MAOB (0.42) | MAOBTDP1CYP1A2NPSR1NR1I2 | |
| SCHEMBL12425733 | 0.83 | CA12 (0.50) | APPCYP19A1NQO2MAOAMAOB | |
| SCHEMBL8661673 | 0.82 | NR1I2 (0.53) | MAOAMAOBLMNACYP1A2CYP3A4 | |
| SCHEMBL5002639 | 0.82 | NR1I2 (0.53) | MAOAMAOBLMNACYP1A2CYP3A4 | |
| SCHEMBL8657360 | 0.81 | GSK3B (0.47) | CYP19A1NQO2MAOBTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670493-A | ANGIOGENESIS INHIBITORS | ADIR ET COMPAGNIE (FR) | 1997-09-23 | — | — | US | disclosed |