Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.57 |
| ▸ | FAP | Q12884 | 2/20 | 0.57 |
| ▸ | ELANE | P08246 | 8/20 | 0.52 |
| ▸ | CTSG | P08311 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 6/20 | 0.51 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.46 |
| ▸ | CMA1 | P23946 | 2/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610923 | 1.00 | PREP (0.57) | PREPFAPELANECTSGACE | |
| SCHEMBL8961434 | 1.00 | PREP (0.57) | PREPFAPELANECTSGACE | |
| SCHEMBL8924728 | 0.90 | CASP1 (0.49) | PREPFAPELANECTSGXIAP | |
| SCHEMBL8924739 | 0.90 | CASP1 (0.49) | PREPFAPELANECTSGXIAP | |
| SCHEMBL8922945 | 0.88 | XIAP (0.54) | ELANECTSGACEXIAPMLX | |
| SCHEMBL8610946 | 0.88 | XIAP (0.54) | ELANECTSGACEXIAPMLX | |
| SCHEMBL8920881 | 0.87 | ELANE (0.46) | PREPFAPELANECTSGXIAP | |
| SCHEMBL8920868 | 0.87 | ELANE (0.46) | PREPFAPELANECTSGXIAP | |
| SCHEMBL8920878 | 0.87 | ELANE (0.46) | PREPFAPELANECTSGXIAP | |
| SCHEMBL8961343 | 0.87 | ELANE (0.46) | PREPFAPELANECTSGXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616573-A | Glucocorticoids | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |