SCHEMBL8922941

SCHEMBL8922941

COc1ccc(O)c(Cc2cc(C)cc(C(C)(C)C)c2O)c1

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.67
CYP2C9 P11712 2/20 0.65
CYP2C19 P33261 2/20 0.65
HIF1A Q16665 2/20 0.65
SMN1; SMN2 Q16637 2/20 0.65
CYP2D6 P10635 1/20 0.58
HSD17B10 Q99714 1/20 0.58
AMY1A P0DUB6 1/20 0.54
CA2 P00918 3/20 0.46
CA1 P00915 2/20 0.46
ALDH1A1 P00352 2/20 0.46
POLB P06746 1/20 0.46
TYR P14679 1/20 0.46
GAA P10253 2/20 0.44
ELANE P08246 1/20 0.40
ALOX5 P09917 1/20 0.40
MTNR1A P48039 1/20 0.39
MTNR1B P49286 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL722580 0.87 HSPA5 (0.77) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
Methoxymethane SCHEMBL9414514 0.83 HSPA5 (0.89) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29415372 0.82 HSPA5 (1.00) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29351672 0.82 HSPA5 (1.00) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL34162 0.82 HSPA5 (1.00) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
Butylated Hydroxytoluene SCHEMBL8847112 0.81 CA2 (0.62) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL3227398 0.80 CA2 (0.71) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29357108 0.80 CYP2C9 (1.00) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29410654 0.80 HSPA5 (0.96) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL11247674 0.80 CYP2C9 (1.00) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0330504-B1 Photosensitive material and image forming method CANON KK (JP) 1996-05-22 EP claimed
EP-0653680-A2 Photosensitive composition, photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1995-05-17 EP claimed
US-5663032-A NAPHTHOL DERIVATIVE REDUCING AGENT CANON KABUSHIKI KAISHA (JP) 1997-09-02 US disclosed
EP-0332455-B1 Photosensitive material and image forming method CANON KK (JP) 1996-06-05 EP disclosed
EP-0330504-B1 Photosensitive material and image forming method CANON KK (JP) 1996-05-22 EP disclosed
EP-0360014-B1 Photosensitive material and image forming method using same CANON KK (JP) 1996-01-03 EP disclosed
EP-0653680-A2 Photosensitive composition, photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1995-05-17 EP disclosed
US-5415974-A Silver halide, organic silver salt, polymerizable compound, heat-diffusing dye CANON KABUSHIKI KAISHA (JP) 1995-05-16 US disclosed
US-5260164-A Silver halide, organic silver salt, cyclic reducing agent, the above compounds adapted to provide imagewise oxidized product of reducing agent upon imagewise exposure and heat development, polymer precursor, photopolymerization initiator CANON KABUSHIKI KAISHA (JP) 1993-11-09 US disclosed
US-5064744-A Heat, photopolymerization, silver halide contrast CANON KABUSHIKI KAISHA (JP) 1991-11-12 US disclosed
US-5041369-A Silver Halide, Silver Salt, Reducing Agent, Metal or Organic Dye CANON KABUSHIKI KAISHA (JP) 1991-08-20 US disclosed
EP-0360014-A1 Photosensitive material and image forming method using same CANON KABUSHIKI KAISHA (JP) 1990-03-28 EP disclosed
EP-0332455-A2 Photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1989-09-13 EP disclosed
EP-0330504-A2 Photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1989-08-30 EP disclosed