Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 3/20 | 0.68 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.66 |
| ▸ | RARA | P10276 | 5/20 | 0.55 |
| ▸ | RARB | P10826 | 5/20 | 0.55 |
| ▸ | RARG | P13631 | 5/20 | 0.55 |
| ▸ | RXRA | P19793 | 5/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925232 | 0.92 | CA9 (0.68) | CA9CHRNA7PTGS2SMN1; SMN2NR1H2 | |
| SCHEMBL9204895 | 0.90 | CA9 (0.82) | CA9CHRNA7ALOX5PTGS2SMN1; SMN2 | |
| SCHEMBL9210036 | 0.90 | CA9 (0.75) | CA9CHRNA7ALOX5PTGS2NR1H2 | |
| SCHEMBL9941326 | 0.90 | CA9 (0.82) | CA9CHRNA7ALOX5PTGS2NR1H2 | |
| SCHEMBL6511261 | 0.88 | CA9 (0.69) | CA9CHRNA7PTGS2SMN1; SMN2 | |
| SCHEMBL7627415 | 0.88 | CHRNA7 (0.83) | CA9CHRNA7PTGS2 | |
| SCHEMBL9199282 | 0.88 | CA9 (0.72) | CA9CHRNA7PTGS2SMN1; SMN2NR1H2 | |
| SCHEMBL9199925 | 0.88 | CA9 (0.68) | CA9CHRNA7PTGS2 | |
| SCHEMBL9202722 | 0.87 | CA9 (0.67) | CA9CHRNA7ALOX5PTGS2SMN1; SMN2 | |
| SCHEMBL9206406 | 0.87 | CA9 (0.67) | CA9CHRNA7PTGS2SMN1; SMN2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670533-A | ANTIINFLAMMATORY AGENTS, ANALGESICS OR ANTIRHEUMATIC DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| US-5550147-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTITHROMBOTIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0554829-A2 | Pyrazole derivatives with antiinflammatory, analgesic and antithrombolic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-11 | — | — | EP | disclosed |