Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Erucic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.85 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.85 |
| ▸ | PPARG | P37231 | 5/20 | 0.85 |
| ▸ | PPARD | Q03181 | 5/20 | 0.85 |
| ▸ | PPARA | Q07869 | 5/20 | 0.85 |
| ▸ | F7 | P08709 | 5/20 | 0.85 |
| ▸ | F3 | P13726 | 5/20 | 0.85 |
| ▸ | TERT | O14746 | 3/20 | 0.85 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.85 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.85 |
| ▸ | FABP4 | P15090 | 3/20 | 0.85 |
| ▸ | TOP1 | P11387 | 3/20 | 0.85 |
| ▸ | MAPT | P10636 | 2/20 | 0.85 |
| ▸ | BLM | P54132 | 2/20 | 0.85 |
| ▸ | LMNA | P02545 | 2/20 | 0.85 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.85 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.85 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.85 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.85 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oleic Acid SCHEMBL1080939 | 1.00 | PPARG (0.85) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL1080934 | 1.00 | PPARG (0.85) | PPARGPPARDPPARAF7F3 | |
| Erucic Acid SCHEMBL8922990 | 1.00 | PPARG (0.85) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL29625346 | 0.98 | PPARG (0.82) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL15533448 | 0.98 | PPARG (0.82) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL28443484 | 0.98 | PPARG (0.82) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL15533452 | 0.98 | PPARG (0.82) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL8883809 | 0.98 | PPARG (0.82) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL7686922 | 0.98 | PPARG (0.82) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL7686916 | 0.98 | PPARG (0.82) | PPARGPPARDPPARAF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652271-A1 | Well fluid additive | BAKER HUGHES INCORPORATED (US) | 1995-05-10 | — | — | EP | claimed |
| US-5658860-A | LUBRICATING DRILL WITH OIL IN WATER EMULSION HAVING WATER PHASE CONTAINING SULFURIZED ALCOHOL DISSOLVED IN WATER SOLUBLE ALCOHOL SOLVENT | BAKER HUGHES INCORPORATED (US) | 1997-08-19 | — | — | US | disclosed |
| US-5586608-A | Method of making an anti-bit balling well fluid using a polyol having a cloud point, and method of drilling | BAKER HUGHES INCORPORATED (US) | 1996-12-24 | — | — | US | disclosed |
| WO-1996040836-A1 | METHOD OF MAKING AN ANTI-BIT BALLING WELL FLUID USING A POLYOL HAVING A CLOUD POINT, AND METHOD OF DRILLING | BAKER HUGHES INCORPORATED (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0652271-A1 | Well fluid additive | BAKER HUGHES INCORPORATED (US) | 1995-05-10 | — | — | EP | disclosed |