Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | TNF | P01375 | 2/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924568 | 0.91 | MME (0.44) | TNFMMEMMEL1PPARGPPARA | |
| SCHEMBL7343190 | 0.84 | KCNA5 (0.45) | KCNA5 | |
| Hydrochloric Acid SCHEMBL7229517 | 0.73 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DTNF | |
| SCHEMBL6184942 | 0.70 | NR1H2 (0.36) | — | |
| SCHEMBL6606177 | 0.67 | CTSA (0.52) | MMEMMEL1SLC13A5 | |
| SCHEMBL7227941 | 0.65 | MME (0.53) | TNFMMEMMEL1PPARGPPARA | |
| SCHEMBL11839726 | 0.65 | PPARG (0.47) | MMEMMEL1PPARGPPARASLC13A5 | |
| SCHEMBL13653511 | 0.65 | AKR1C3 (0.50) | MMEMMEL1PPARGPPARASLC13A5 | |
| SCHEMBL6607584 | 0.65 | MME (0.53) | TNFMMEMMEL1PPARGPPARA | |
| SCHEMBL9451503 | 0.65 | DPP4 (0.41) | MMEMMEL1PPARGPPARASLC13A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660840-B1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA GEIGY AG (CH) | 1997-05-07 | — | — | EP | disclosed |
| US-5550119-A | ENDOTHELIN-CONVERTING ENZYM INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1996-08-27 | — | — | US | disclosed |