Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | MDH1 | P40925 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038498 | 0.90 | ADRA2A (0.55) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL8921452 | 0.88 | ADRA2A (0.58) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL7811157 | 0.86 | ADRA2A (0.54) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL9539611 | 0.86 | ADRA2A (0.51) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL9036400 | 0.86 | ADRA2A (0.53) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL5197662 | 0.85 | ADRA2A (0.70) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL8985916 | 0.85 | ADRA2A (0.53) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL9036267 | 0.85 | ADRA2A (0.53) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL9037116 | 0.84 | ADRA2A (0.53) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL5109661 | 0.84 | ADRA2A (0.53) | ADRA2AADORA3CHRM1MAOATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599930-A | Substituted indoles as anti-AIDS pharmaceuticals | THE UPJOHN COMPANY (US) | 1997-02-04 | — | — | US | claimed |