Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460819 | 0.90 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL8925421 | 0.89 | PTGS2 (0.81) | PTGS2PTGS1ABCB11ALDH1A1 | |
| SCHEMBL7463018 | 0.89 | PTGS2 (0.81) | PTGS2PTGS1ABCB11ALDH1A1 | |
| SCHEMBL7462312 | 0.85 | PTGS2 (0.65) | PTGS2PTGS1ABCB11ALDH1A1 | |
| SCHEMBL7462246 | 0.84 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL8954509 | 0.83 | PTGS2 (0.80) | PTGS2PTGS1 | |
| SCHEMBL8953911 | 0.83 | PTGS2 (0.73) | PTGS2PTGS1ABCB11ALDH1A1 | |
| SCHEMBL8954050 | 0.83 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL9003118 | 0.83 | PTGS2 (0.73) | PTGS2PTGS1ABCB11ALDH1A1 | |
| SCHEMBL8635509 | 0.82 | PTGS2 (0.78) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670533-A | ANTIINFLAMMATORY AGENTS, ANALGESICS OR ANTIRHEUMATIC DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| US-5550147-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTITHROMBOTIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0554829-A2 | Pyrazole derivatives with antiinflammatory, analgesic and antithrombolic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-11 | — | — | EP | disclosed |