Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923310 | 1.00 | MEN1 (0.65) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL1430608 | 0.87 | MEN1 (0.73) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL794085 | 0.87 | MEN1 (0.73) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL9344811 | 0.81 | MEN1 (0.69) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL838875 | 0.81 | MEN1 (0.72) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL30545232 | 0.81 | MEN1 (0.72) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL838874 | 0.81 | MEN1 (0.72) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL352750 | 0.81 | SLC7A5 (0.62) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL30960537 | 0.81 | SLC7A5 (0.62) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL180092 | 0.81 | SLC7A5 (0.62) | SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668121-A | Glutamate (NMDA) receptor antagonists | WARNER-LAMBERT COMPANY (US) | 1997-09-16 | — | — | US | claimed |
| US-5668121-A | Glutamate (NMDA) receptor antagonists | WARNER-LAMBERT COMPANY (US) | 1997-09-16 | — | — | US | disclosed |
| US-5489717-A | Glutamate (NMDA) receptor antagonists | WARNER-LAMBERT COMPANY | 1996-02-06 | — | — | US | disclosed |